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A Spanish animation about Alzheimer’s disease, set in a care home, this bleak, funny, sympathetic and desperately sad film is based on a comic book by Paco Roca.

Redubbed here by an American cast led by a brilliantly bewildered Martin Sheen, its shuffling pace and basic animation all add to the heartbreak as the protagonists slowly unravel, even as they fight to keep a grip.

At one point the old folk make an ill-fated break for freedom, and their confusion, defiance, fear and longing for a normal, dignified life make this nothing less than Juan Flew Over The Cuckoo’s Nest .